United paid £35m for the Netherlands international, 26, three years ago, however, he has failed to make an impression in the Premier League.
Not even the arrival of his former Ajax boss Erik ten Hag last year has turned the situation around.
Van de Beek started on the squad during last Sunday’s final pre-season game against Athletic Bilbao in Dublin but was subbed at half-time. He is viewed as one of the several unproductive players United is eager to offload to raise money for Erik ten Hag to strengthen his team this summer.
Goalkeeper Dean Henderson has the option of returning to Nottingham Forest, where he was on loan during the previous season. However, his situation is complicated by a thigh injury he sustained in January, which has prohibited him from participating in any preseason games.
Defender Eric Bailly of the Ivory Coast has been informed he may need to find a new club and that Ten Hag’s plans do not include him.
Fred, a midfielder for Brazil, is still a target for Fulham, although no definite offer has yet been made.